Paroxetine induced bruxism, treated with Buspirone : An unexplored entity

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Paroxetine induced bruxism, treated with Buspirone : An unexplored entity

SSRI are the widely prescribed first line drugs for depression and as depression very commonly presents with insomnia SSRI are good at improving the sleep problems also. But though rare the occurrence of sleep related side effects like bruxism,it may cause significant distress and cause of nonadherence which easily may be overlooked. In this case we report a case of Paroxetine induced bruxism a...

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Paroxetine-induced severe sleep bruxism successfully treated with buspirone

Sleep bruxism is characterized by the involuntary clenching or grinding of the teeth during sleep and can cause severe health problems, including the destruction of tooth structure, temporo-mandibular joint dysfunction, myofascial pain, and severe sleep disturbances (1). Iatrogenic sleep bruxism may be common during treatment with pyschotropic medications, such as antipsychotics and antidepress...

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Antidepressant-induced bruxism: need for buspirone?

Bruxism is an involuntary grinding of the teeth which can occur during daytime or night. An estimated 85–90% of the population brux at some time during their lives, but it is clinically significant in only 5% of them. In such cases it can result in significant periodontal damage and can produce significant sleep disturbance in the bed partner of the person (Moore et al., 2000). Reports of SSRI-...

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Paroxetine‐induced QTc prolongation

There have been only two previous reports of paroxetine-induced corrected QT (QTc) prolongation on electrocardiogram (ECG). Here, we report a 43-year-old woman with QTc prolongation (476 ms). She had taken 50 mg of paroxetine for 17 days. Three days after discontinuation of paroxetine, QTc returned to within the normal limits (396 ms). Paroxetine blocks the human ether-a-go-go-related gene (HER...

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Platelet reactivity in depressed patients treated with paroxetine: preliminary findings.

BACKGROUND Alterations in platelet reactivity have been previously posited to underlie the increased vulnerability of patients with depression to ischemic heart disease (IHD). The present study sought to determine whether the increased platelet reactivity associated with major depression is reduced after antidepressant treatment. METHODS Patients diagnosed as having DSM-IV major depression (n...

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ژورنال

عنوان ژورنال: Bengal Journal of Psychiatry

سال: 2014

ISSN: 2348-9227

DOI: 10.51332/bjp.2014.v19.i1.63